Pan Am Flight 103 was a regularly scheduled Pan Am transatlantic flight from Frankfurt to Detroit via London and New York .

On 21 December 1988 , N739PA , the aircraft operating Control the transatlantic leg of the route was destroyed Destroying by a bomb , killing Killing all 243 passengers and 16 crew – a disaster known as the Lockerbie bombing .

Flight 607-E departed Departing Shannon at 03:05 UTC on the second leg of a transatlantic trip from Amsterdam to New York City with intermediate stops in Shannon and Gander , Newfoundland .